Perfil de gestantes acometidas de parto prematuro em uma maternidade pública / Profile of the pregnant women affected by preterm birthing a public maternity hospital / Perfil de la mujer embarazada de trabajo afectada prematura en una maternidad pública

Objetivo: Caracterizar o perfil das gestantes acometidas de parto prematuro; descrever as complicações do parto prematuro; identificar o número de óbitos por parto prematuro. Método: Pesquisa retrospectiva; transversal com abordagem quantitativa; realizada em uma maternidade pública, a amostra que representou a população constituiu-se de 300 prontuários de gestantes com parto prematuro. Pesquisa aprovada pelo Comitê de Ética; sob CAAE nº 47429315.1.0000.5210. Resultados: Faixa etária predominante foi 14 a 19 anos 26,38%; escolaridade ensino médio (56,68%); situação conjugal casada (38,11%); ocupação do lar (48,21%); raça não registrada (99,67%); local de moradia zona rural (57,00%). Maior incidência de complicações dentro das variáveis; foram pré-eclâmpsia (28,66%); amniorrexe prematura (17,26%). Causa maior de óbito: Pré-eclâmpsia. Conclusão: Destaca-se que pré-eclâmpsia foi o agravo que causou o maior número de óbitos nas mulheres investigadas; esse dado evidencia as estatísticas alarmantes; confirmando que as doenças hipertensivas ocupam o primeiro lugar como causa de morte materna no Brasil

Objetivo: Caracterizar el perfil de parto prematuro afectaba a lãs mujeres embarazadas; describir lãs complicaciones Del nacimiento prematuro; identificar el número de muertes debidas al parto prematuro. Método: Estudio retrospectivo; cruzar com un enfoque cuantitativo; realizado em un hospital público, La muestra que representa la población constaba de 300 historias clínicas de mujeres embarazadas com trabajo de parto prematuro. De investigacióna probado por el Comité de Ética, La opinión Nº 1.175.971. Resultados: Rango de edad predominante fue de 14 a 19 años 26,38%; educación secundaria (56,68%); estado civil casada (38,11%); ocupación de la casa (48,21%); No raza registrado (99,67%); lugar de residencia, rural (57.00%). Mayor incidencia de complicaciones en las variables y preeclampsia (28,66%); ruptura prematura de membranas (17,26%). Principal causa de muerte: La pre-eclampsia. Conclusión: Es de destacar que La preeclampsia fue La lesión que causo el mayor número de muertes investigadas em lãs mujeres; estos datos pone de manifiesto las estadísticas alarmantes; lo que confirma que lãs enfermedades hipertensivas ocupan el primer lugar como causa de muerte materna en Brasil

Objective: Herein, our goal has been to characterize the pregnant women profile that experienced preterm birth. Moreover, describe the complications of preterm birth, and also to identify the number of deaths due to preterm birth. Methods: It is a retrospective cohort study with a quantitative approach, whichwas carried out in a public maternity hospital. The sample that represented the population consisted of 300 medical records of pregnant women with preterm birth. The research was approved by the Ethics Committee under the Legal Opinion No. 1,175,971. Results: The predominant age group was from 14 to 19 years old (26.38%); high school education (56.68%); married (38.11%); housekeeper (48.21%); unregistered race (99.67%); rural area as residence place (57.00%). The following were the higher incidence of complications within the variables: pre-eclampsia(28.66%) and premature amniorrexis (17.27%). The major cause of death was pre-eclampsia. Conclusion: It should be noted that pre-eclampsia caused the highest number of deaths in the women investigated and this fact shows the alarming statistics, confirming that hypertensive diseases occupy the first place as cause of maternal death in Brazil

Intra-Amniotic Infection/Inflammation as a Risk Factor for Subsequent Ruptured Membranes after Clinically Indicated Amniocentesis in Preterm Labor

The aim of this study was to determine whether intra-amniotic infection/inflammation (IAI) was associated with subsequent ruptured membranes in women with preterm labor and intact membranes who had a clinically indicated amniocentesis. This retrospective cohort study included 237 consecutive women with preterm labor (20-34.6 weeks) who underwent amniocentesis. The clinical and laboratory parameters evaluated included demographic variables, gestational age, C-reactive protein (CRP) and amniotic fluid (AF) white blood cell, interleukin-6 (IL-6) and culture results. IAI was defined as a positive AF culture and/or an elevated AF IL-6 level (>2.6 ng/mL). The primary outcome was ruptured membranes in the absence of active labor occurring within 48 hours of amniocentesis. Preterm premature rupture of membranes subsequently developed in 10 (4.2%) women within 48 hr of amniocentesis. Multivariate analysis demonstrated that only IAI was independently associated with the ruptured membranes occurring within 48 hr of amniocentesis. In the predictive model based on variables assessed before amniocentesis, only CRP level was retained. IAI is an independent risk factor for subsequent ruptured membranes after clinically indicated amniocentesis in preterm labor. Prior to amniocentesis, measurement of serum CRP level can provide a risk assessment for the subsequent development of ruptured membranes after the procedure.

Membrana amniótica como alternativa de tratamiento en superficie ocular / Amniotic membrane as a therapeutic option for the ocular surface

Se realizó una revisión bibliográfica con el objetivo de conocer la utilidad de la membrana amniótica como alternativa de tratamiento en la superficie ocular. Son abordados tópicos como las diferentes formas de obtención, preparación y conservación de la misma, sus mecanismos de acción y aplicaciones. Se consultó una bibliografía que abarca un periodo de varios años para conocer los resultados publicados sobre el trasplante de membrana amniótica humana en la superficie ocular. ..

A literature review was made to learn about the usefulness of the amniotic membrane as a therapeutic option for the ocular surface. The different ways for obtaining, preparing, and conserving this membrane, its mechanism of action and its applications were also addressed. Literature covering several years was reviewed in order to be acquainted with the published results of the human amniotic membrane transplantation on the ocular surface...

Fisiopatología de la rotura prematura de las membranas ovulares em embarazos de pretérmino / Physiopathology of the premature rupture of membranes in preterm pregnancies

Se revisa la información de la literatura respecto de la estructura de las membranas ovulares, describiendo la zona de morfología alterada extrema, los mecanismos fisiopatológicos involucrados en la rotura prematura de membranas (destacando el proceso de apoptosis), relacionados a infección, isquemia placentaria, distensión de membranas, hemorragia coriodecidual, tabaquismo, relaxina, prolactina, hormona paratiroídea.